Linyee Shum
Publications by Year
Research Areas
Antibiotics Pharmacokinetics and Efficacy, Pharmacology and Obesity Treatment, Analytical Methods in Pharmaceuticals, Pharmacogenetics and Drug Metabolism, HIV/AIDS drug development and treatment
Most-Cited Works
- → Oral administration of DuP 753, a specific angiotensin II receptor antagonist, to normal male volunteers. Inhibition of pressor response to exogenous angiotensin I and II.(1991)249 cited
- → Cyclic HIV Protease Inhibitors: Synthesis, Conformational Analysis, P2/P2‘ Structure−Activity Relationship, and Molecular Recognition of Cyclic Ureas(1996)170 cited
- → Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450(1996)148 cited
- → Initial Human Experience with Ganaxolone, a Neuroactive Steroid with Antiepileptic Activity(1997)124 cited
- → Simultaneous determination of pioglitazone and its two active metabolites in human plasma by LC–MS/MS(2003)93 cited
- → Simultaneous determination of glipizide and rosiglitazone unbound drug concentrations in plasma by equilibrium dialysis and liquid chromatography–tandem mass spectrometry(2003)61 cited
- → Simultaneous determination of glycyrrhizin, a marker component in radix Glycyrrhizae, and its major metabolite glycyrrhetic acid in human plasma by LC–MS/MS(2004)52 cited
- → Amphiphilic vehicles improve the oral bioavailability of a poorly soluble HIV protease inhibitor at high doses1Portions of this work were presented at Journeé Galéniques de Saint-Rémy de Provence, May 1994, and at the AAPS Eastern Regional Meeting, June 1994.1(1997)46 cited
- → In vitro plasma protein binding determination of flunarizine using equilibrium dialysis and liquid chromatography–tandem mass spectrometry(2005)21 cited
- → Theophylline tissue partitioning and volume of distribution in normal and dietary‐induced obese rats(1987)18 cited