Alexandra Borodovsky
Nurix (United States)(US)
Publications by Year
Research Areas
Adenosine and Purinergic Signaling, Cancer Immunotherapy and Biomarkers, Glioma Diagnosis and Treatment, Epigenetics and DNA Methylation, Hedgehog Signaling Pathway Studies
Most-Cited Works
- → Itraconazole and Arsenic Trioxide Inhibit Hedgehog Pathway Activation and Tumor Growth Associated with Acquired Resistance to Smoothened Antagonists(2013)333 cited
- → Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine(2013)236 cited
- → 5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft(2013)154 cited
- → Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade(2020)116 cited
- → Repurposing the Antihelmintic Mebendazole as a Hedgehog Inhibitor(2014)102 cited
- → Adenosine Signaling Is Prognostic for Cancer Outcome and Has Predictive Utility for Immunotherapeutic Response(2020)97 cited
- → Small molecule AZD4635 inhibitor of A2AR signaling rescues immune cell function including CD103+ dendritic cells enhancing anti-tumor immunity(2020)97 cited
- → Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2(2011)72 cited
- → Demethylation and epigenetic modification with 5-azacytidine reduces IDH1 mutant glioma growth in combination with temozolomide(2018)70 cited
- → Targeting adenosine A2A receptor antagonism for treatment of cancer(2018)54 cited