James S. Frazee
Publications by Year
Research Areas
Organic Chemistry Cycloaddition Reactions, Synthesis and Reactions of Organic Compounds, Synthesis and biological activity, Estrogen and related hormone effects, Chemical Synthesis and Reactions
Most-Cited Works
- → SB 209670, a rationally designed potent nonpeptide endothelin receptor antagonist.(1994)163 cited
- → Orally Active and Potent Inhibitors of γ-Aminobutyric Acid Uptake(1985)130 cited
- → Some benzyl-substituted imidazoles, triazoles, tetrazoles, pyridinethiones, and structural relatives as multisubstrate inhibitors of dopamine .beta.-hydroxylase. 4. Structure-activity relationships at the copper binding site(1990)47 cited
- → Synthesis and antiviral activity of a novel class of HIV-1 protease inhibitors containing a heterocyclic P1′-P2′ amide bond isostere(1994)45 cited
- → Multisubstrate inhibitors of dopamine .beta.-hydroxylase. 2. Structure-activity relationships at the phenethylamine binding site(1987)45 cited
- → High-affinity leukotriene receptor antagonists. Synthesis and pharmacological characterization of 2-hydroxy-3-[(2-carboxyethyl)thio]-3-[2-(8-phenyloctyl)phenyl]propanoic acid(1987)44 cited
- → Stereospecific synthesis of C-6(7) methoxypenicillin and cephalosporin derivatives(1973)44 cited
- → Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors(2009)43 cited
- → Substituted 1-benzylimidazole-2-thiols as potent and orally active inhibitors of dopamine .beta.-hydroxylase(1986)40 cited
- → ChemInform Abstract: ORALLY ACTIVE AND POTENT INHIBITORS OF Γ‐AMINOBUTYRIC ACID UPTAKE(1985)37 cited