René Hemmig
Novartis (Switzerland)(CH)Novartis Foundation(CH)
Publications by Year
Research Areas
Bone health and treatments, Radiopharmaceutical Chemistry and Applications, Immune Response and Inflammation, Organophosphorus compounds synthesis, Biochemical and Molecular Research
Most-Cited Works
- → Structural Basis for the Exceptional in vivo Efficacy of Bisphosphonate Drugs(2006)223 cited
- → Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery(2010)123 cited
- → Expression, Refolding, and Autocatalytic Proteolytic Processing of the Interleukin-1β-converting Enzyme Precursor(1995)107 cited
- → NMR Reporter Screening for the Detection of High-Affinity Ligands(2002)99 cited
- → Increased Mature Interleukin-1β (IL-1β) Secretion from THP-1 Cells Induced by Nigericin Is a Result of Activation of p45 IL-1β-converting Enzyme Processing(1998)77 cited
- → The X-ray Crystal Structure of the First RNA Recognition Motif and Site-Directed Mutagenesis Suggest a Possible HuR Redox Sensing Mechanism(2010)45 cited
- → IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling(2022)28 cited
- → Ranking of High‐Affinity Ligands by NMR Spectroscopy(2009)24 cited
- → A General Strategy for Targeting Drugs to Bone(2015)23 cited
- → Therapeutic potential of allosteric HECT E3 ligase inhibition(2025)18 cited