Shibi Likhite
Publications by Year
Research Areas
Neurogenetic and Muscular Disorders Research, RNA modifications and cancer, CRISPR and Genetic Engineering, Amyotrophic Lateral Sclerosis Research, Virus-based gene therapy research
Most-Cited Works
- → Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy(2017)2,265 cited
- → Astrocytes from familial and sporadic ALS patients are toxic to motor neurons(2011)777 cited
- → Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS(2013)349 cited
- → Improving Single Injection CSF Delivery of AAV9-mediated Gene Therapy for SMA: A Dose–response Study in Mice and Nonhuman Primates(2014)273 cited
- → Therapeutic AAV9-mediated Suppression of Mutant SOD1 Slows Disease Progression and Extends Survival in Models of Inherited ALS(2013)199 cited
- → Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism(2016)180 cited
- → Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis(2016)141 cited
- → Delayed Disease Onset and Extended Survival in the SOD1G93ARat Model of Amyotrophic Lateral Sclerosis after Suppression of Mutant SOD1 in the Motor Cortex(2014)132 cited
- → Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease(2019)54 cited
- → Optimization and validation of CAR transduction into human primary NK cells using CRISPR and AAV(2022)52 cited