Brian D. Hamman
Publications by Year
Research Areas
RNA and protein synthesis mechanisms, Protein Degradation and Inhibitors, Chromatin Remodeling and Cancer, Pain Mechanisms and Treatments, Peptidase Inhibition and Analysis
Most-Cited Works
- → Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead(2017)876 cited
- → Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase(2019)507 cited
- → BiP Maintains the Permeability Barrier of the ER Membrane by Sealing the Lumenal End of the Translocon Pore before and Early in Translocation(1998)424 cited
- → Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming Toxin Clostridium perfringens Perfringolysin O: An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy(1998)318 cited
- → The Aqueous Pore through the Translocon Has a Diameter of 40–60 Å during Cotranslational Protein Translocation at the ER Membrane(1997)278 cited
- → Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1(2017)249 cited
- → A FRET-Based Assay Platform for Ultra-High Density Drug Screening of Protein Kinases and Phosphatases(2002)159 cited
- → Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers(2022)121 cited
- → Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain(2016)119 cited
- → Novel Class of LIM-Kinase 2 Inhibitors for the Treatment of Ocular Hypertension and Associated Glaucoma(2009)77 cited