David H. Rominger
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, Pharmacological Receptor Mechanisms and Effects, Hormonal Regulation and Hypertension, Computational Drug Discovery Methods
Most-Cited Works
- → A G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with Morphine(2013)639 cited
- → Quantifying Ligand Bias at Seven-Transmembrane Receptors(2011)389 cited
- → Selectively Engaging β-Arrestins at the Angiotensin II Type 1 Receptor Reduces Blood Pressure and Increases Cardiac Performance(2010)364 cited
- → Presenilin-1 and -2 Are Molecular Targets for γ-Secretase Inhibitors(2000)301 cited
- → Myelosuppression and kinase selectivity of multikinase angiogenesis inhibitors(2009)218 cited
- → Structure–Activity Relationships and Discovery of a G Protein Biased μ Opioid Receptor Ligand, [(3-Methoxythiophen-2-yl)methyl]({2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro-[4.5]decan-9-yl]ethyl})amine (TRV130), for the Treatment of Acute Severe Pain(2013)196 cited
- → Divergent Transducer-specific Molecular Efficacies Generate Biased Agonism at a G Protein-coupled Receptor (GPCR)(2014)131 cited
- → Two New Potent Neurotransmitter Release Enhancers, 10,10-Bis(4-Pyridinylmethyl)-9(10H)-Anthracenone and 10,10-Bis(2-Fluoro-4-Pyridinylmethyl)-9(10H)-Anthracenone: Comparison to Linopirdine(1998)130 cited
- → Biased mu-opioid receptor ligands: a promising new generation of pain therapeutics(2016)126 cited
- → Characterization of [125I]Sauvagine Binding to CRH2 Receptors: Membrane Homogenate and Autoradiographic Studies(1998)65 cited