Linda Stein

Publications by Year

Research Areas

Peroxisome Proliferator-Activated Receptors, Protein Kinase Regulation and GTPase Signaling, Receptor Mechanisms and Signaling, Metabolism, Diabetes, and Cancer, Adipose Tissue and Metabolism

Most-Cited Works

• → Design and Synthesis of a Novel and Potent Series of Inhibitors of Cytosolic Phospholipase A₂ Based on a 1,3-Disubstituted Propan-2-one Skeleton(2002)84 cited
• → Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate(2014)54 cited
• → Discovery of isoindoline and tetrahydroisoquinoline derivatives as potent, selective PPARδ agonists(2010)30 cited
• → Scaffold-hopping with zwitterionic CCR3 antagonists: Identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092(2012)20 cited
• → Synthesis of benzimidazole based JNK inhibitors(2005)14 cited
• → Synthesis and evaluation of substrate-mimicking cytosolic phospholipase A2 inhibitors––reducing the lipophilicity of the arachidonyl chain isostere(2004)14 cited
• → Synthesis and biological evaluation of N-alkylated 8-oxybenz[c]azepine derivatives as selective PPARδ agonists(2010)11 cited