Lawrence MacPherson
Broad Institute(US)Howard Hughes Medical Institute(US)
Publications by Year
Research Areas
Osteoarthritis Treatment and Mechanisms, Antifungal resistance and susceptibility, Protease and Inhibitor Mechanisms, Antiplatelet Therapy and Cardiovascular Diseases, Synthesis and properties of polymers
Most-Cited Works
- → Discovery of CGS 27023A, a Non-Peptidic, Potent, and Orally Active Stromelysin Inhibitor That Blocks Cartilage Degradation in Rabbits(1997)325 cited
- → Development of small-molecule probes that selectively kill cells induced to express mutant RAS(2011)234 cited
- → Pyrrolamide DNA Gyrase Inhibitors: Fragment-Based Nuclear Magnetic Resonance Screening To Identify Antibacterial Agents(2011)134 cited
- → Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes(2009)84 cited
- → Natural Selection, Protein Engineering, and the Last Riboorganism: Rational Model Building in Biochemistry(1987)70 cited
- → A Direct Route to 3‐(D‐Ribofuranosyl)pyridine Nucleosides(1991)53 cited
- → Redesigning nucleic acids(1998)52 cited
- → Potent and selective inhibitors of Helicobacter pylori glutamate racemase (MurI): Pyridodiazepine amines(2008)49 cited
- → Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor(2012)45 cited
- → Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies(2012)40 cited