Brian F. Clem
University of Louisville Hospital(US)
Publications by Year
Research Areas
Cancer, Hypoxia, and Metabolism, Cancer-related Molecular Pathways, Epigenetics and DNA Methylation, Metabolism, Diabetes, and Cancer, RNA modifications and cancer
Most-Cited Works
- → Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth(2008)431 cited
- → Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer(2009)401 cited
- → Targeting aspartate aminotransferase in breast cancer(2008)288 cited
- → Targeting 6-Phosphofructo-2-Kinase (PFKFB3) as a Therapeutic Strategy against Cancer(2013)274 cited
- → Nuclear Targeting of 6-Phosphofructo-2-kinase (PFKFB3) Increases Proliferation via Cyclin-dependent Kinases(2009)240 cited
- → Lactate supports a metabolic-epigenetic link in macrophage polarization(2021)233 cited
- → Control of glutamine metabolism by the tumor suppressor Rb(2013)208 cited
- → 6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27(2014)203 cited
- → Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer(2016)105 cited
- → Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism(2014)100 cited