Jeffrey J. Hale
Greenfield Research (Canada)(CA)
Publications by Year
Research Areas
Sphingolipid Metabolism and Signaling, Neuropeptides and Animal Physiology, HIV Research and Treatment, HIV/AIDS drug development and treatment, Chemical Synthesis and Analysis
Most-Cited Works
- → Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists(2002)1,677 cited
- → Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors(1998)1,075 cited
- → Immune Cell Regulation and Cardiovascular Effects of Sphingosine 1-Phosphate Receptor Agonists in Rodents Are Mediated via Distinct Receptor Subtypes(2004)333 cited
- → Sphingosine 1-phosphate receptor agonists attenuate relapsing–remitting experimental autoimmune encephalitis in SJL mice(2004)223 cited
- → Structural Optimization Affording 2-(R)-(1-(R)-3,5-Bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist(1998)203 cited
- → Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties(2005)148 cited
- → In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists(1997)117 cited
- → Discovery of Potent 3,5-Diphenyl-1,2,4-oxadiazole Sphingosine-1-phosphate-1 (S1P1) Receptor Agonists with Exceptional Selectivity against S1P2 and S1P3(2005)99 cited
- → Phosphorylated Morpholine Acetal Human Neurokinin-1 Receptor Antagonists as Water-Soluble Prodrugs(2000)95 cited
- → A Rational Utilization of High-Throughput Screening Affords Selective, Orally Bioavailable 1-Benzyl-3-carboxyazetidine Sphingosine-1-phosphate-1 Receptor Agonists(2004)88 cited