Koen Brusselmans
Sciensano (Belgium)(BE)
Publications by Year
Research Areas
Cancer, Lipids, and Metabolism, Cancer, Hypoxia, and Metabolism, Lipid metabolism and biosynthesis, Microtubule and mitosis dynamics, Peroxisome Proliferator-Activated Receptors
Most-Cited Works
- → Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis(1998)2,486 cited
- → Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration(2001)1,009 cited
- → Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice(2002)728 cited
- → De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation(2010)705 cited
- → Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188(1999)681 cited
- → Increased lipogenesis in cancer cells: new players, novel targets(2006)616 cited
- → Induction of Cancer Cell Apoptosis by Flavonoids Is Associated with Their Ability to Inhibit Fatty Acid Synthase Activity(2004)463 cited
- → Chemical Inhibition of Acetyl-CoA Carboxylase Induces Growth Arrest and Cytotoxicity Selectively in Cancer Cells(2007)314 cited
- → Heterozygous deficiency of hypoxia-inducible factor–2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia(2003)308 cited
- RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells.(2003)