Patrick S. Ward
Publications by Year
Research Areas
Epigenetics and DNA Methylation, Acute Myeloid Leukemia Research, Cancer, Hypoxia, and Metabolism, Glioma Diagnosis and Treatment, Histone Deacetylase Inhibitors Research
Most-Cited Works
- → Cancer-associated IDH1 mutations produce 2-hydroxyglutarate(2009)4,077 cited
- → Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate(2012)3,226 cited
- → Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation(2010)2,713 cited
- → IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype(2012)1,973 cited
- → The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate(2010)1,966 cited
- → IDH mutation impairs histone demethylation and results in a block to cell differentiation(2012)1,943 cited
- → MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations(2020)1,871 cited
- → Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability(2011)962 cited
- → Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation(2012)424 cited