Vaishali Shinde
Institute for Learning and Development(US)
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Cancer-related Molecular Pathways, Ubiquitin and proteasome pathways, Protein Degradation and Inhibitors, Neuroblastoma Research and Treatments
Most-Cited Works
- → Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays(2011)300 cited
- → A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models(2021)131 cited
- → Localization of Human TACC3 to Mitotic Spindles Is Mediated by Phosphorylation on Ser558 by Aurora A: A Novel Pharmacodynamic Method for Measuring Aurora A Activity(2007)128 cited
- → Phase I Study of the Selective Aurora A Kinase Inhibitor MLN8054 in Patients with Advanced Solid Tumors: Safety, Pharmacokinetics, and Pharmacodynamics(2010)86 cited
- → Ubiquitin-activating enzyme inhibition induces an unfolded protein response and overcomes drug resistance in myeloma(2019)75 cited
- → Characterization of the Loss of SUMO Pathway Function on Cancer Cells and Tumor Proliferation(2015)60 cited
- → Plk1 Inhibition Causes Post-Mitotic DNA Damage and Senescence in a Range of Human Tumor Cell Lines(2014)60 cited
- → Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905)(2011)54 cited
- → TAK-676: A Novel Stimulator of Interferon Genes (STING) Agonist Promoting Durable IFN-dependent Antitumor Immunity in Preclinical Studies(2022)51 cited
- → Phase I Assessment of New Mechanism-Based Pharmacodynamic Biomarkers for MLN8054, a Small-Molecule Inhibitor of Aurora A Kinase(2010)46 cited