Thorsten Oost
Boehringer Ingelheim (Austria)(AT)
Publications by Year
Research Areas
RNA Interference and Gene Delivery, Cell death mechanisms and regulation, DNA and Nucleic Acid Chemistry, Receptor Mechanisms and Signaling, Botulinum Toxin and Related Neurological Disorders
Most-Cited Works
- → Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain(2000)636 cited
- → Discovery of Potent Antagonists of the Antiapoptotic Protein XIAP for the Treatment of Cancer(2004)364 cited
- → Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL(2007)294 cited
- → Discovery and Structure−Activity Relationship of Antagonists of B-Cell Lymphoma 2 Family Proteins with Chemopotentiation Activity in Vitro and in Vivo(2006)130 cited
- → Discovery of Aminoglycoside Mimetics by NMR-Based Screening of Escherichia c oli A-site RNA(2003)80 cited
- → Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR(2010)71 cited
- → Potent, selective inhibitors of protein tyrosine phosphatase 1B(2003)48 cited
- → Potent and selective oxindole-based vasopressin 1b receptor antagonists with improved pharmacokinetic properties(2011)46 cited
- → Synthesis of substrates and inhibitors of botulinum neurotoxin type A metalloprotease*(2004)37 cited
- → Structural Basis for BABIM Inhibition of Botulinum Neurotoxin Type B Protease(2000)30 cited