Kevin Yang
Skåne University Hospital(SE)
Publications by Year
Research Areas
Protein Kinase Regulation and GTPase Signaling, Autophagy in Disease and Therapy, PI3K/AKT/mTOR signaling in cancer, Skin Protection and Aging, Melanoma and MAPK Pathways
Most-Cited Works
- → Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors(2019)691 cited
- → Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors(2011)119 cited
- → Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRASG12C(2019)103 cited
- → Structure-Based Design of Novel Class II c-Met Inhibitors: 2. SAR and Kinase Selectivity Profiles of the Pyrazolone Series(2012)74 cited
- → Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations(2022)67 cited
- → Outcomes of pancreaticoduodenectomy for pancreatic malignancy in octogenarians: an American College of Surgeons National Surgical Quality Improvement Program analysis(2013)61 cited
- → Phospshoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Discovery and Structure–Activity Relationships of a Series of Quinoline and Quinoxaline Derivatives(2011)60 cited
- → Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 3. Structure–Activity Relationships within the Aryl Carbinol Region of the N-Arylsulfonamido-N′-arylpiperazine Series(2014)52 cited
- → A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B(2018)51 cited
- → Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511(2012)50 cited