Jan Klapwijk
South College(US)GlaxoSmithKline (United States)(US)
Publications by Year
Research Areas
Animal testing and alternatives, Cardiac electrophysiology and arrhythmias, Inhalation and Respiratory Drug Delivery, Pharmacogenetics and Drug Metabolism, Metabolomics and Mass Spectrometry Studies
Most-Cited Works
- → 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile(2006)190 cited
- → The selection of marmoset monkeys (Callithrix jacchus) in pharmaceutical toxicology(2001)95 cited
- → Challenges for inhaled drug discovery and development: Induced alveolar macrophage responses(2014)90 cited
- → Spontaneous Cardiomyopathy in Young Sprague-Dawley Rats(2013)38 cited
- → Imaging drugs, metabolites and biomarkers in rodent lung: a DESI MS strategy for the evaluation of drug-induced lipidosis(2019)32 cited
- → Morphometric Characterization of Rat and Human Alveolar Macrophage Cell Models and their Response to Amiodarone using High Content Image Analysis(2017)17 cited
- → Comparison of Oral, Intranasal and Aerosol Administration of Amiodarone in Rats as a Model of Pulmonary Phospholipidosis(2019)14 cited
- → Good Laboratory Practice Preclinical Safety Studies for GSK2696273 (MLV Vector-Based Ex Vivo Gene Therapy for Adenosine Deaminase Deficiency Severe Combined Immunodeficiency) in NSG Mice(2017)13 cited
- → The exploration of aza-quinolines as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors with low brain exposure(2020)10 cited
- → A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 1 of 2)(2017)9 cited