Janelle Comita-Prevoir
Entasis Therapeutics (United States)(US)
Publications by Year
Research Areas
Antibiotic Resistance in Bacteria, Antibiotics Pharmacokinetics and Efficacy, Cancer therapeutics and mechanisms, Tuberculosis Research and Epidemiology, Protein Structure and Dynamics
Most-Cited Works
- → ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii(2017)267 cited
- → Rational design of a new antibiotic class for drug-resistant infections(2021)137 cited
- → Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II: Broad-Spectrum Antibacterial Agents with Reduced hERG Activity(2011)101 cited
- → Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced pKa: Antibacterial Agents with an Improved Safety Profile(2012)89 cited
- → Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C, and D Serine β-Lactamases(2020)59 cited
- → Potent and selective inhibitors of Helicobacter pylori glutamate racemase (MurI): Pyridodiazepine amines(2008)49 cited
- → Exploring Left-Hand-Side substitutions in the benzoxazinone series of 4-amino-piperidine bacterial type IIa topoisomerase inhibitors(2011)31 cited
- → Exploring 8-benzyl pteridine-6,7-diones as inhibitors of glutamate racemase (MurI) in Gram-positive bacteria(2008)27 cited
- → Optimization of physicochemical properties and safety profile of novel bacterial topoisomerase type II inhibitors (NBTIs) with activity against Pseudomonas aeruginosa(2014)24 cited
- → Exploring 9-benzyl purines as inhibitors of glutamate racemase (MurI) in Gram-positive bacteria(2008)20 cited