Brad Loe
La Roche College(US)
Publications by Year
Research Areas
Synthesis of Organic Compounds, Melanoma and MAPK Pathways, Synthesis and biological activity, Photochromic and Fluorescence Chemistry, Quinazolinone synthesis and applications
Most-Cited Works
- → Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as Orally Bioavailable and Highly Selective Inhibitors of p38α Mitogen-Activated Protein Kinase(2011)74 cited
- → Topical nonsteroidal antipsoriatic agents. 1. 1,2,3,4-Tetraoxygenated naphthalene derivatives(1986)29 cited
- → 3-Amino-pyrazolo[3,4-d]pyrimidines as p38α kinase inhibitors: Design and development to a highly selective lead(2011)27 cited
- → Novel Series of Dihydropyridinone P2X7 Receptor Antagonists(2015)27 cited
- → Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): Optimization for JNK potency and physicochemical properties(2013)18 cited
- → Topical nonsteroidal antipsoriatic agents. 2. 2,3-(Alkylidenedioxy)naphthalene analogs of lonapalene(1988)18 cited
- → ChemInform Abstract: Topical Nonsteroidal Antipsoriatic Agents. Part 1. 1,2,3,4‐Tetraoxygenated Naphthalene Derivatives.(1987)1 cited
- → Additions and Corrections - Topical Nonsteroidal Antipsoriatic Agents. 1. 1,2,3,4-Tetraoxygenated Naphthalene Derivatives.(1986)
- → ChemInform Abstract: Topical Nonsteroidal Antipsoriatic Agents. Part 2. 2,3‐(Alkylidenedioxy)naphthalene Analogues of Lonapalene.(1989)
- → CCDC 1432897: Experimental Crystal Structure Determination(2015)