Laura E. Randle
University of Liverpool(GB)
Publications by Year
Research Areas
Drug-Induced Hepatotoxicity and Protection, Cholangiocarcinoma and Gallbladder Cancer Studies, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Liver physiology and pathology
Most-Cited Works
- → Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice(2004)203 cited
- → Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver(2010)168 cited
- → Isoquine and Related Amodiaquine Analogues: A New Generation of Improved 4-Aminoquinoline Antimalarials(2003)142 cited
- → The hepatotoxic metabolite of acetaminophen directly activates the Keap1‐Nrf2 cell defense system†(2008)131 cited
- → The Generation, Detection, and Effects of Reactive Drug Metabolites(2012)86 cited
- → The Metabolism and Toxicity of Furosemide in the Wistar Rat and CD-1 Mouse: a Chemical and Biochemical Definition of the Toxicophore(2007)71 cited
- → Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice(2007)55 cited
- → Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes(2005)40 cited
- → Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome(2015)38 cited
- → α1‐Adrenoceptor antagonists prevent paracetamol‐induced hepatotoxicity in mice(2007)37 cited