Mark A. Bobko
South College(US)
Publications by Year
Research Areas
Synthesis and biological activity, Chemical Synthesis and Analysis, PI3K/AKT/mTOR signaling in cancer, Melanoma and MAPK Pathways, Protein Kinase Regulation and GTPase Signaling
Most-Cited Works
- → Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach(2001)85 cited
- → Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors(2011)54 cited
- → Solid-phase synthesis of a library of piperazinediones and diazepinediones via kaiser oxime resin(1998)51 cited
- → Discovery and SAR of novel Naphthyridines as potent inhibitors of spleen tyrosine kinase (SYK)(2003)48 cited
- → Discovery of a new class of p38 kinase inhibitors(2000)47 cited
- → 5,7-Dimethoxy-3-(4-Pyridinyl)Quinoline Is a Potent and Selective Inhibitor of Human Vascular .beta.-Type Platelet-Derived Growth Factor Receptor Tyrosine Kinase(1994)41 cited
- → Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)(2008)32 cited
- → Isolation and structure elucidation of two new calpain inhibitors from Streptomyces griseus.(1994)29 cited
- → Structure, determination, pharmacological evaluation, and structure-activity studies of a new cyclic peptide substance P antagonist containing the new amino acid 3-prenyl-.beta.-hydroxytyrosine isolated from Aspergillus flavipes(1994)23 cited
- → Synthesis, Characterization, and Conformational Analysis of the D/L-Tic7 Stereoisomers of Bradykinin Receptor Antagonist D-Arg0[Hyp3,Thi5,D-Tic7,Oic8]bradykinin(1994)20 cited