Patrick J. Grohar
Van Andel Institute(US)Children's Hospital of Philadelphia(US)University of Michigan(US)Michigan Medicine(US)C. S. Mott Children's Hospital(US)
Publications by Year
Research Areas
Sarcoma Diagnosis and Treatment, RNA modifications and cancer, Protein Degradation and Inhibitors, RNA Research and Splicing, Ubiquitin and proteasome pathways
Most-Cited Works
- → Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism(2006)746 cited
- → Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening(2011)202 cited
- → Ecteinascidin 743 Interferes with the Activity of EWS-FLI1 in Ewing Sarcoma Cells(2011)121 cited
- → Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus(2016)87 cited
- → Dual Targeting of EWS-FLI1 Activity and the Associated DNA Damage Response with Trabectedin and SN38 Synergistically Inhibits Ewing Sarcoma Cell Growth(2013)83 cited
- → Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children’s Oncology Group (COG) New Agents for Ewing Sarcoma Task Force(2019)83 cited