Nicola M. Heron
Publications by Year
Research Areas
Asymmetric Synthesis and Catalysis, Microtubule and mitosis dynamics, Synthetic Organic Chemistry Methods, Cancer-related Molecular Pathways, Asymmetric Hydrogenation and Catalysis
Most-Cited Works
- → AZD1152, a Selective Inhibitor of Aurora B Kinase, Inhibits Human Tumor Xenograft Growth by Inducing Apoptosis(2007)356 cited
- → Discovery, Synthesis, and in Vivo Activity of a New Class of Pyrazoloquinazolines as Selective Inhibitors of Aurora B Kinase(2007)273 cited
- → SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors(2005)125 cited
- → Catalytic and Enantioselective Route to Medium-Ring Heterocycles. Asymmetric Zirconium-Catalyzed Ethylmagnesation of Seven- and Eight-Membered Rings(1996)112 cited
- → Discovery of Novel and Potent Thiazoloquinazolines as Selective Aurora A and B Kinase Inhibitors(2006)92 cited
- → Ni-Catalyzed Asymmetric Addition of Grignard Reagents to Unsaturated Cyclic Acetals. The Influence of Added Phosphine on Enantioselectivity(1998)89 cited
- → Progress in the Development of Selective Inhibitors of Aurora Kinases(2005)75 cited
- → Discovery of an Orally Bioavailable NK1 Receptor Antagonist, (2S,3S)-(2-Methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine (GR203040), with Potent Antiemetic Activity(1995)52 cited
- → Stereoselective Heteroatom-Assisted Allylic Alkylation of Cyclic Ethers with Grignard Reagents. A Convenient Route to Enantiomerically Pure Carbocycles(1997)47 cited
- → (1R,2R)-N-(1-Cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): A Potent and Highly Selective Cathepsin K Inhibitor for the Treatment of Osteoarthritis(2012)39 cited