S. de Kimpe
ProQR Therapeutics (Netherlands)(NL)
Publications by Year
Research Areas
Muscle Physiology and Disorders, RNA Interference and Gene Delivery, RNA Research and Splicing, Nitric Oxide and Endothelin Effects, Advanced biosensing and bioanalysis techniques
Most-Cited Works
- → Mechanism of Gram-positive Shock: Identification of Peptidoglycan and Lipoteichoic Acid Moieties Essential in the Induction of Nitric Oxide Synthase, Shock, and Multiple Organ Failure(1998)242 cited
- → Guidelines for Antisense Oligonucleotide Design and Insight Into Splice-modulating Mechanisms(2008)146 cited
- → Preclinical PK and PD Studies on 2′-O-Methyl-phosphorothioate RNA Antisense Oligonucleotides in the mdx Mouse Model(2010)137 cited
- → Species-specific Inflammatory Responses as a Primary Component for the Development of Glomerular Lesions in Mice and Monkeys Following Chronic Administration of a Second-generation Antisense Oligonucleotide(2013)57 cited
- → Placebo‐controlled Phase 2 Trial of Drisapersen for Duchenne Muscular Dystrophy(2018)35 cited
- → Albumin restores lysophosphatidylcholine-induced inhibition of vasodilation in rat aorta(2001)30 cited
- → Evaluation of serum MMP-9 as predictive biomarker for antisense therapy in Duchenne(2017)29 cited
- → The Pharmacokinetics of 2′- O -Methyl Phosphorothioate Antisense Oligonucleotides: Experiences from Developing Exon Skipping Therapies for Duchenne Muscular Dystrophy(2019)26 cited
- → Inhibition of IL-1 Signaling by Antisense Oligonucleotide-mediated Exon Skipping of IL-1 Receptor Accessory Protein (IL-1RAcP)(2013)20 cited
- → Preclinical Studies on Intestinal Administration of Antisense Oligonucleotides as a Model for Oral Delivery for Treatment of Duchenne Muscular Dystrophy(2014)15 cited