Nicholas D. Mazarakis
Imperial College London(GB)
Publications by Year
Research Areas
Virus-based gene therapy research, RNA Interference and Gene Delivery, Nerve injury and regeneration, Multiple Sclerosis Research Studies, CRISPR and Genetic Engineering
Most-Cited Works
- → VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model(2004)591 cited
- → Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model(2005)499 cited
- → Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial(2014)434 cited
- → Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery(2001)422 cited
- → Stable gene transfer to the nervous system using a non-primate lentiviral vector(1999)282 cited
- → Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase(2010)243 cited
- → Multicistronic Lentiviral Vector-Mediated Striatal Gene Transfer of Aromatic l-Amino Acid Decarboxylase, Tyrosine Hydroxylase, and GTP Cyclohydrolase I Induces Sustained Transgene Expression, Dopamine Production, and Functional Improvement in a Rat Model of Parkinson's Disease.(2002)219 cited
- → Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy(2004)198 cited
- → Lentivirus-Mediated Gene Transfer to the Central Nervous System: Therapeutic and Research Applications(2006)183 cited
- → Dopamine Gene Therapy for Parkinson’s Disease in a Nonhuman Primate Without Associated Dyskinesia(2009)178 cited