Steven B. Coffey
Pfizer (United States)(US)
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Chemical Synthesis and Analysis, Catalytic C–H Functionalization Methods, Neuropeptides and Animal Physiology, Click Chemistry and Applications
Most-Cited Works
- → Palladium-Catalyzed Sulfination of Aryl and Heteroaryl Halides: Direct Access to Sulfones and Sulfonamides(2013)225 cited
- → Reaction of Alkyl Halides with Rongalite: One-Pot and Telescoped Syntheses of Aliphatic Sulfonamides, Sulfonyl Fluorides, and Unsymmetrical Sulfones(2016)103 cited
- → Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)(2015)81 cited
- → Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose(2020)69 cited
- → Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2(2009)58 cited
- → Maximizing Lipophilic Efficiency: The Use of Free-Wilson Analysis in the Design of Inhibitors of Acetyl-CoA Carboxylase(2011)54 cited
- → Preparation of Heteroaryl Ethers from Azine N-Oxides and Alcohols(2016)53 cited
- → Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK)(2017)49 cited
- → Amidation of esters assisted by Mg(OCH3)2 or CaCl2(2010)49 cited
- → Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists(2012)47 cited