Alison E. Varghese
Pfizer (United States)(US)
Publications by Year
Research Areas
Neuropeptides and Animal Physiology, CRISPR and Genetic Engineering, Receptor Mechanisms and Signaling, Protein Structure and Dynamics, Antibiotic Resistance in Bacteria
Most-Cited Works
- → SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1(2010)890 cited
- → Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing(2018)153 cited
- → Spirocyclic Sulfamides as β-Secretase 1 (BACE-1) Inhibitors for the Treatment of Alzheimer’s Disease: Utilization of Structure Based Drug Design, WaterMap, and CNS Penetration Studies To Identify Centrally Efficacious Inhibitors(2012)60 cited
- → An inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism(2023)32 cited
- → Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4(2022)19 cited
- → Structural basis of the acyl-transfer mechanism of human GPAT1(2022)14 cited
- Cytotoxic Escherichia coli.(1987)
- Cytopathic effects of shigellae on Vero & HeLa cells.(1983)
- → Receptor‐Mediated Delivery of CRISPR‐Cas9 Endonuclease for Cell Type Specific Gene Editing(2018)
- → An inverse agonist of orphan receptor GPR61 reveals a novel allosteric mechanism(2023)