James Palacino
Fulcrum Therapeutics (United States)(US)
Publications by Year
Research Areas
RNA Research and Splicing, RNA modifications and cancer, RNA and protein synthesis mechanisms, Nitric Oxide and Endothelin Effects, Genetic Neurodegenerative Diseases
Most-Cited Works
- → Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle(1994)1,697 cited
- → Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice(2004)996 cited
- → Parkin-deficient Mice Exhibit Nigrostriatal Deficits but Not Loss of Dopaminergic Neurons(2003)910 cited
- → Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits.(1994)495 cited
- → Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types(2018)472 cited
- → SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice(2015)426 cited
- → Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins(2016)352 cited
- → Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations(2018)212 cited
- → Direct association of presenilin‐1 with β‐catenin(1998)156 cited
- → Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex(2017)148 cited