Thomas Helleday
Karolinska University Hospital(SE)Science for Life Laboratory(SE)Weston Park Cancer Centre(GB)Karolinska Institutet(SE)University of Sheffield(GB)
Publications by Year
Research Areas
DNA Repair Mechanisms, PARP inhibition in cancer therapy, CRISPR and Genetic Engineering, Epigenetics and DNA Methylation, Cancer-related Molecular Pathways
Most-Cited Works
- → Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase(2005)5,108 cited
- → Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints(2006)1,951 cited
- → DNA repair pathways as targets for cancer therapy(2008)1,663 cited
- → Replication stress links structural and numerical cancer chromosomal instability(2013)904 cited
- → Mechanisms underlying mutational signatures in human cancers(2014)863 cited
- → The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings(2011)827 cited