Anne M. Exall

Publications by Year

Research Areas

HIV/AIDS drug development and treatment, Carbohydrate Chemistry and Synthesis, Biochemical and Molecular Research, Synthesis of β-Lactam Compounds, Neuroendocrine regulation and behavior

Most-Cited Works

• → The discovery of GSK221149A: A potent and selective oxytocin antagonist(2007)91 cited
• → Pyridyl-2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists: Synthesis, Pharmacokinetics, and In Vivo Potency(2012)89 cited
• → Design and Synthesis of Pyrrolidine-5,5‘-trans-Lactams (5-Oxo-hexahydropyrrolo[3,2-b]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 4. Antiviral Activity and Plasma Stability(2003)72 cited
• → Design and Synthesis of Pyrrolidine-5,5-trans-lactams (5-Oxohexahydropyrrolo[3,2-b]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 2. Potency and Chirality(2001)72 cited
• → 2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: identification, stereochemistry and initial SAR(2005)66 cited
• → Synthesis and enzymatic resolution of carbocyclic 2′-ara-fluoro-guanosine: a potent new anti-herpetic agent(1988)59 cited
• → Fluoro carbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluoro carbocyclic pyrimidine nucleosides including carbocyclic 1-(2-deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-methyluracil and carbocyclic 1-(2-deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-iodouracil(1990)57 cited
• → 2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists. 2. Synthesis, Chirality, and Pharmacokinetics(2005)53 cited
• → Fluorocarbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic 2'-deoxyguanosines(1991)52 cited
• → Use of diethylaminosulphur trifluoride (DAST) in the preparation of synthons of carbocyclic nucleosides(1988)52 cited