John H. Hutchinson
Publications by Year
Research Areas
Asthma and respiratory diseases, Inflammatory mediators and NSAID effects, Receptor Mechanisms and Signaling, Neuroscience and Neuropharmacology Research, Synthetic Organic Chemistry Methods
Most-Cited Works
- → Pharmacokinetic and Pharmacodynamic Characterization of an Oral Lysophosphatidic Acid Type 1 Receptor-Selective Antagonist(2010)126 cited
- → Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)-indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor(1992)113 cited
- → Nonpeptide αvβ3 Antagonists. 8. In Vitro and in Vivo Evaluation of a Potent αvβ3 Antagonist for the Prevention and Treatment of Osteoporosis(2003)96 cited
- → Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an Inhibitor Selective for LOXL2 over LOX(2017)82 cited
- → Nonpeptide αvβ3 Antagonists. Part 11: Discovery and Preclinical Evaluation of Potent αvβ3 Antagonists for the Prevention and Treatment of Osteoporosis(2004)79 cited
- → Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding(2015)66 cited
- → Novel Strategies for the Construction of Complex Polycyclic Ether Frameworks. Stereocontrolled Synthesis of the FGHIJ Ring System of Brevetoxin A(1991)66 cited
- → Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2)(2017)65 cited
- → Non-Peptide Glycoprotein IIb/IIIa Antagonists. 11. Design and in Vivo Evaluation of 3,4-Dihydro-1(1H)-isoquinolinone-Based Antagonists and Ethyl Ester Prodrugs(1996)64 cited
- → Total Synthesis of Brevetoxin A: Part 3: Construction of GHIJ and BCDE Ring Systems(1999)58 cited