Olivier René
NovaBay Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Catalytic Cross-Coupling Reactions, Catalytic C–H Functionalization Methods, Retinoids in leukemia and cellular processes, Fluorine in Organic Chemistry, Sulfur-Based Synthesis Techniques
Most-Cited Works
- → Room-Temperature Direct Arylation of Polyfluorinated Arenes under Biphasic Conditions(2010)193 cited
- → Domino Palladium-Catalyzed Heck-Intermolecular Direct Arylation Reactions(2009)132 cited
- → Evaluation of Electron‐Deficient Phosphine Ligands for Direct Arylation of Heterocycles(2010)86 cited
- → Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action(2014)82 cited
- → Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc(2013)62 cited
- → Discovery of 1-{4-[3-Fluoro-4-((3 S ,6 R )-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C (RORc or RORγ) Inverse Agonist(2015)59 cited
- → Reduction in lipophilicity improved the solubility, plasma–protein binding, and permeability of tertiary sulfonamide RORc inverse agonists(2014)49 cited
- → Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections(2023)38 cited
- → A reversed sulfonamide series of selective RORc inverse agonists(2014)35 cited
- → Efficient syntheses of 2-fluoroalkylbenzimidazoles and -benzothiazoles(2012)33 cited