Jiemin Lu
Pfizer (United States)(US)
Publications by Year
Research Areas
Phosphodiesterase function and regulation, Chemical Synthesis and Analysis, Cholinesterase and Neurodegenerative Diseases, Chemical synthesis and alkaloids, Computational Drug Discovery Methods
Most-Cited Works
- → Design and Selection Parameters to Accelerate the Discovery of Novel Central Nervous System Positron Emission Tomography (PET) Ligands and Their Application in the Development of a Novel Phosphodiesterase 2A PET Ligand(2013)199 cited
- → Discovery, SAR, and Pharmacokinetics of a Novel 3-Hydroxyquinolin-2(1H)-one Series of Potentd-Amino Acid Oxidase (DAAO) Inhibitors(2009)109 cited
- → Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor(2017)32 cited
- → 3-Benzyl-1,3-oxazolidin-2-ones as mGluR2 positive allosteric modulators: Hit-to lead and lead optimization(2009)32 cited
- → Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate(2018)27 cited
- Identification of a predictive efficacy signature from microarray analysis of human tumor xenografts treated with anticancer compounds.(2004)