Jessica Frankum
Institute of Cancer Research(GB)Breast Cancer Now(GB)
Publications by Year
Research Areas
PARP inhibition in cancer therapy, BRCA gene mutations in cancer, CRISPR and Genetic Engineering, DNA Repair Mechanisms, Cancer Genomics and Diagnostics
Most-Cited Works
- → The shieldin complex mediates 53BP1-dependent DNA repair(2018)641 cited
- → Germline mutations in RAD51D confer susceptibility to ovarian cancer(2011)531 cited
- → Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance(2018)438 cited
- → Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity(2013)363 cited
- → Clinical BRCA1/2 Reversion Analysis Identifies Hotspot Mutations and Predicted Neoantigens Associated with Therapy Resistance(2020)174 cited
- → The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells(2018)159 cited
- → Functional Viability Profiles of Breast Cancer(2011)142 cited
- → E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer(2018)129 cited
- → Synthetic lethality of PARP and NAMPT inhibition in triple‐negative breast cancer cells(2012)125 cited
- → High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing(2011)123 cited