Georgia B. McGaughey
United States Military Academy(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Protein Structure and Dynamics, Enzyme Structure and Function, HIV Research and Treatment, Receptor Mechanisms and Signaling
Most-Cited Works
- → π-Stacking Interactions(1998)1,138 cited
- → Comparison of Topological, Shape, and Docking Methods in Virtual Screening(2007)415 cited
- → Discovery of the Dual Orexin Receptor Antagonist [(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia(2010)370 cited
- → Molecular Shape and Medicinal Chemistry: A Perspective(2010)310 cited
- → D3R grand challenge 4: blind prediction of protein–ligand poses, affinity rankings, and relative binding free energies(2020)141 cited
- → Discovery of 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor with Improved Potency against Key Mutant Viruses(2008)132 cited
- → Discovery of [(2R,5R)‐5‐{[(5‐Fluoropyridin‐2‐yl)oxy]methyl}‐2‐methylpiperidin‐1‐yl][5‐methyl‐2‐(pyrimidin‐2‐yl)phenyl]methanone (MK‐6096): A Dual Orexin Receptor Antagonist with Potent Sleep‐Promoting Properties(2012)121 cited
- → First Demonstration of Cerebrospinal Fluid and Plasma Aβ Lowering with Oral Administration of a β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor in Nonhuman Primates(2008)105 cited
- → HIV-1 Vaccine Development: Constrained Peptide Immunogens Show Improved Binding to the Anti-HIV-1 gp41 MAb(2003)101 cited
- → Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs)(2007)88 cited