Marc Abrams
Dicerna Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
RNA Interference and Gene Delivery, MicroRNA in disease regulation, RNA modifications and cancer, RNA Research and Splicing, Advanced biosensing and bioanalysis techniques
Most-Cited Works
- Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.(2001)
- → Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment(2009)206 cited
- → Kinesin Spindle Protein (KSP) Inhibitors. 9. Discovery of (2S)-4-(2,5-Difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the Treatment of Taxane-Refractory Cancer(2008)156 cited
- → Hepatocyte‐Specific β‐Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes(2018)140 cited
- → Phosphorylation of Linker Histone H1 Regulates Gene Expression In Vivo by Mimicking H1 Removal(1999)138 cited
- → Expression of Asialoglycoprotein Receptor 1 in Human Hepatocellular Carcinoma(2013)123 cited
- → Inhibition of Glucocorticoid-induced Apoptosis by Targeting the Major Splice Variants of BIM mRNA with Small Interfering RNA and Short Hairpin RNA(2004)121 cited
- → RNAi-Mediated β-Catenin Inhibition Promotes T Cell Infiltration and Antitumor Activity in Combination with Immune Checkpoint Blockade(2018)121 cited
- → Biodistribution of Small Interfering RNA at the Organ and Cellular Levels after Lipid Nanoparticle-mediated Delivery(2011)120 cited
- Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor.(2000)