Paul D. van Poelje
Publications by Year
Research Areas
Cancer, Hypoxia, and Metabolism, Biochemical and Molecular Research, Metabolism, Diabetes, and Cancer, HIV/AIDS drug development and treatment, Hepatitis B Virus Studies
Most-Cited Works
- → Targeting thyroid hormone receptor-β agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index(2007)262 cited
- → PYRUVOYL-DEPENDENT ENZYMES(1990)242 cited
- → Isolation of a Family of Organic Anion Transporters from Human Liver and Kidney(2001)219 cited
- → Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist #(2008)204 cited
- → MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes(2005)162 cited
- → Discovery of a Series of Phosphonic Acid-Containing Thiazoles and Orally Bioavailable Diamide Prodrugs That Lower Glucose in Diabetic Animals Through Inhibition of Fructose-1,6-Bisphosphatase(2010)159 cited
- → Design, Synthesis, and Characterization of a Series of Cytochrome P4503A-Activated Prodrugs (HepDirect Prodrugs) Useful for Targeting Phosph(on)ate-Based Drugs to the Liver§(2004)157 cited
- → Liver-Targeted Drug Delivery Using HepDirect Prodrugs(2005)117 cited
- → Discovery of Potent and Specific Fructose-1,6-Bisphosphatase Inhibitors and a Series of Orally-Bioavailable Phosphoramidase-Sensitive Prodrugs for the Treatment of Type 2 Diabetes(2007)96 cited
- → A Potent and Selective AMPK Activator That Inhibits de Novo Lipogenesis(2010)91 cited