Ray Unwalla
Pfizer (United States)(US)
Publications by Year
Research Areas
Cytokine Signaling Pathways and Interactions, Computational Drug Discovery Methods, Estrogen and related hormone effects, Monoclonal and Polyclonal Antibodies Research, Protein Structure and Dynamics
Most-Cited Works
- → Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition(2016)191 cited
- → Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases(2018)163 cited
- → Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans(2017)160 cited
- → Fluorine in Drug Design: A Case Study with Fluoroanisoles(2015)149 cited
- → Synthesis and Structure−Activity Relationship of Novel 6-Aryl-1,4- dihydrobenzo[d][1,3]oxazine-2-thiones as Progesterone Receptor Modulators Leading to the Potent and Selective Nonsteroidal Progesterone Receptor Agonist Tanaproget(2005)91 cited
- → Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors(2018)74 cited
- → Comprehensive Assessment of Torsional Strain in Crystal Structures of Small Molecules and Protein–Ligand Complexes using ab Initio Calculations(2019)54 cited
- → (1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine: A Wingless β-Catenin Agonist That Increases Bone Formation Rate(2009)52 cited
- → Millisecond dynamics of BTK reveal kinome-wide conformational plasticity within the apo kinase domain(2017)50 cited
- → Development of QSAR models for microsomal stability: identification of good and bad structural features for rat, human and mouse microsomal stability(2009)48 cited