Christopher J. Helal
Biogen (United States)(US)Pfizer (United States)(US)
Publications by Year
Research Areas
Phosphodiesterase function and regulation, Cholinesterase and Neurodegenerative Diseases, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Chemical Synthesis and Analysis
Most-Cited Works
- → Reduction of Carbonyl Compounds with Chiral Oxazaborolidine Catalysts: A New Paradigm for Enantioselective Catalysis and a Powerful New Synthetic Method(1998)1,300 cited
- → A platform for automated nanomole-scale reaction screening and micromole-scale synthesis in flow(2018)481 cited
- → Reduktion von Carbonylverbindungen mit chiralen Oxazaborolidin-Katalysatoren: eine neue enantioselektive Katalyse und leistungsfähige Synthesemethode(1998)384 cited
- → Design and Selection Parameters to Accelerate the Discovery of Novel Central Nervous System Positron Emission Tomography (PET) Ligands and Their Application in the Development of a Novel Phosphodiesterase 2A PET Ligand(2013)199 cited
- → Novel electronic effects of remote substituents on the oxazaborolidine-catalyzed enantioselective reduction of ketones(1995)157 cited
- → Direct Catalytic Enantioselective Reduction of Achiral α,β-Ynones. Strong Remote Steric Effects Across the C−C Triple Bond