Leonard W. Rozamus
Publications by Year
Research Areas
Signaling Pathways in Disease, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Crystallography and molecular interactions, Bioactive Compounds and Antitumor Agents
Most-Cited Works
- → Redesigning an FKBP–ligand interface to generate chemical dimerizers with novel specificity(1998)559 cited
- → Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer(2004)270 cited
- → Design, synthesis, and kinetic evaluation of high-affinity FKBP ligands and the X-ray crystal structures of their complexes with FKBP12(1993)203 cited
- → DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS, AND THE X-RAY CRYSTAL STRUCTURES OF THEIR COMPLEXES WITH FKBP12(1993)148 cited
- → Investigating Protein−Ligand Interactions with a Mutant FKBP Possessing a Designed Specificity Pocket(2000)92 cited
- → Structure-activity studies of rapamycin analogs: evidence that the C-7 methoxy group is part of the effector domain and positioned at the FKBP12-FRAP interface(1995)41 cited
- → Structure-activity studies of synthetic FKBP ligands as peptidyl-prolyl isomerase inhibitors(1994)31 cited
- → Protein Phosphorylation and Signal Transduction Modulation: Chemistry Perspectives for Small-Molecule Drug Discovery(2005)30 cited
- Structure-based design of AP23573, a phosphorus-containing analog of rapamycin for anti-tumor therapy.(2004)
- → Manipulation of the Rapamycin Effector Domain. Selective Nucleophilic Substitution of the C7 Methoxy Group(1994)21 cited