Douglas M. Sammond

Publications by Year

Research Areas

Asymmetric Synthesis and Catalysis, Alzheimer's disease research and treatments, Synthesis and biological activity, HIV/AIDS drug development and treatment, Drug Transport and Resistance Mechanisms

Most-Cited Works

• → Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: The discovery of GW0385(2006)78 cited
• → Spirocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: From Hit to Lowering of Cerebrospinal Fluid (CSF) Amyloid β in a Higher Species(2013)58 cited
• → Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors(2009)40 cited
• → Discovery of 7-Tetrahydropyran-2-yl Chromans: β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors That Reduce Amyloid β-Protein (Aβ) in the Central Nervous System(2014)38 cited
• → Discovery of a novel and potent series of dianilinopyrimidineurea and urea isostere inhibitors of VEGFR2 tyrosine kinase(2005)30 cited
• → A mild synthesis of substituted furans from γ-hydroxy-α,β-unsaturated ketones(1996)29 cited
• → Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines as EGFR and ErbB-2 inhibitors(2008)20 cited
• → Dihydroxylation and oxidative cleavage of olefins in the presence of sulfur(1996)16 cited
• → Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors(2005)11 cited
• → Ground-state rotational constants of Ar+3 by rotational depletion coherence spectroscopy(1993)9 cited