Stephen Tirrell
Publications by Year
Research Areas
Gene expression and cancer classification, Ubiquitin and proteasome pathways, MicroRNA in disease regulation, Microtubule and mitosis dynamics, Molecular Biology Techniques and Applications
Most-Cited Works
- → A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment(2018)441 cited
- → Phase I Study of the Novel Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/Refractory Multiple Myeloma or Lymphoma(2015)188 cited
- → Ubiquitin-activating enzyme inhibition induces an unfolded protein response and overcomes drug resistance in myeloma(2019)75 cited
- → The beagle dog MicroRNA tissue atlas: identifying translatable biomarkers of organ toxicity(2016)71 cited
- → Comparison of the Predictive Accuracy of DNA Array-Based Multigene Classifiers across cDNA Arrays and Affymetrix GeneChips(2005)50 cited
- → Phase I Assessment of New Mechanism-Based Pharmacodynamic Biomarkers for MLN8054, a Small-Molecule Inhibitor of Aurora A Kinase(2010)46 cited
- → Phase 1 study of ixazomib, an investigational proteasome inhibitor, in advanced non-hematologic malignancies(2015)42 cited
- → Reproducibility of Gene Expression Signature–Based Predictions in Replicate Experiments(2006)34 cited
- → Transcriptional Responses to Estrogen and Progesterone in Mammary Gland Identify Networks Regulating p53 Activity(2008)28 cited
- → Applications of Pathology-Assisted Image Analysis of Immunohistochemistry-Based Biomarkers in Oncology(2013)23 cited