Alexandra D. Gurzau
The University of Melbourne(AU)Walter and Eliza Hall Institute of Medical Research(AU)
Publications by Year
Research Areas
Genomics and Chromatin Dynamics, RNA modifications and cancer, RNA Research and Splicing, Genetics and Neurodevelopmental Disorders, DNA Repair Mechanisms
Most-Cited Works
- → De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development(2017)132 cited
- → SMCHD1 is involved inde novomethylation of theDUX4-encoding D4Z4 macrosatellite(2019)58 cited
- → FSHD2- and BAMS-associated mutations confer opposing effects on SMCHD1 function(2018)48 cited
- → Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid–binding residues(2020)25 cited
- → Relating SMCHD1 structure to its function in epigenetic silencing(2020)22 cited
- → SMCHD1 has separable roles in chromatin architecture and gene silencing that could be targeted in disease(2023)18 cited
- → SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization(2021)7 cited
- SMCHD1 is involved in de novo methylation of the DUX4-encoding D4Z4 macrosatellite(2019)
- → MORC2 is a phosphorylation-dependent DNA compaction machine(2025)3 cited