Irene Feingold
Publications by Year
Research Areas
Cholesterol and Lipid Metabolism, Drug Transport and Resistance Mechanisms, Estrogen and related hormone effects, Sphingolipid Metabolism and Signaling, Hypothalamic control of reproductive hormones
Most-Cited Works
- → LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse(2009)106 cited
- → Indazole-Based Liver X Receptor (LXR) Modulators with Maintained Atherosclerotic Lesion Reduction Activity but Diminished Stimulation of Hepatic Triglyceride Synthesis(2008)75 cited
- → 3-(3-Aryloxyaryl)imidazo[1,2-a]pyridine sulfones as liver X receptor agonists(2009)60 cited
- → Improvement of Physiochemical Properties of the Tetrahydroazepinoindole Series of Farnesoid X Receptor (FXR) Agonists: Beneficial Modulation of Lipids in Primates(2010)53 cited
- → Discovery and SAR of cinnolines/quinolines as liver X receptor (LXR) agonists with binding selectivity for LXRβ(2009)51 cited
- → Discovery of Phenyl Acetic Acid Substituted Quinolines as Novel Liver X Receptor Agonists for the Treatment of Atherosclerosis(2006)50 cited
- → Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells(2008)43 cited
- → Identification of Phenylsulfone-Substituted Quinoxaline (WYE-672) as a Tissue Selective Liver X-receptor (LXR) Agonist(2010)38 cited
- → Further modification on phenyl acetic acid based quinolines as liver X receptor modulators(2007)36 cited
- → Correlating Efficacy in Rodent Cognition Models with in Vivo 5-Hydroxytryptamine1A Receptor Occupancy by a Novel Antagonist, (R)-N-(2-Methyl-(4-indolyl-1-piperazinyl)ethyl)-N-(2-pyridinyl)-cyclohexane Carboxamide (WAY-101405)(2008)35 cited