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Melanie Spears | doi.page

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Melanie Spears

Ontario Institute for Cancer Research(CA)University of Toronto(CA)

Publications by Year

Research Areas

Advanced Breast Cancer Therapies, HER2/EGFR in Cancer Research, Cancer Genomics and Diagnostics, Breast Cancer Treatment Studies, Cancer-related Molecular Pathways

Most-Cited Works

→ Benchmarking to the Gold Standard: Hyaluronan‐Oxime Hydrogels Recapitulate Xenograft Models with In Vitro Breast Cancer Spheroid Culture(2019)81 cited
→ In situ detection of HER2:HER2 and HER2:HER3 protein–protein interactions demonstrates prognostic significance in early breast cancer(2011)70 cited
→ ISOWN: accurate somatic mutation identification in the absence of normal tissue controls(2017)55 cited
→ Deregulation of the spindle assembly checkpoint is associated with paclitaxel resistance in ovarian cancer(2018)34 cited
→ Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer(2016)34 cited
→ The potential role of estrogen receptors and the SRC family as targets for the treatment of breast cancer(2009)32 cited

→ Proximity ligation assays for isoform‐specific Akt activation in breast cancer identify activated Akt1 as a driver of progression(2012)

30 cited

→ In situ quantification of HER2–protein tyrosine kinase 6 (PTK6) protein–protein complexes in paraffin sections from breast cancer tissues(2010)29 cited

→ Molecular characterisation of isogenic taxane resistant cell lines identify novel drivers of drug resistance(2014)27 cited

→ The p160 ER co-regulators predict outcome in ER negative breast cancer(2011)17 cited