Andrea Basso
University of Padua(IT)
Publications by Year
Research Areas
Trace Elements in Health, Microtubule and mitosis dynamics, Heavy Metal Exposure and Toxicity, Genetics, Aging, and Longevity in Model Organisms, Cancer-related Molecular Pathways
Most-Cited Works
- → BRAF mutation predicts sensitivity to MEK inhibition(2005)1,325 cited
- → Akt Forms an Intracellular Complex with Heat Shock Protein 90 (Hsp90) and Cdc37 and Is Destabilized by Inhibitors of Hsp90 Function(2002)622 cited
- The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells.(2001)
- → Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors(2003)453 cited
- → V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors(2005)308 cited
- → Thematic review series: Lipid Posttranslational Modifications. Farnesyl transferase inhibitors(2005)296 cited
- Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3'-kinase/Akt pathway signaling.(2003)