Jack Sadowsky
PDL BioPharma (United States)(US)
Publications by Year
Research Areas
Monoclonal and Polyclonal Antibodies Research, HER2/EGFR in Cancer Research, Cell Adhesion Molecules Research, Chemical Synthesis and Analysis, Protein Degradation and Inhibitors
Most-Cited Works
- → LRRC15+ myofibroblasts dictate the stromal setpoint to suppress tumour immunity(2022)357 cited
- → Ring-Closing Metathesis of Olefinic Peptides: Design, Synthesis, and Structural Characterization of Macrocyclic Helical Peptides(2001)222 cited
- → Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity(2019)185 cited
- → Chimeric (α/β + α)-Peptide Ligands for the BH3-Recognition Cleft of Bcl-x L : Critical Role of the Molecular Scaffold in Protein Surface Recognition(2005)166 cited
- → (α/β+α)-Peptide Antagonists of BH3 Domain/Bcl-xL Recognition: Toward General Strategies for Foldamer-Based Inhibition of Protein−Protein Interactions(2006)165 cited
- → Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy(2021)161 cited
- → Turning a protein kinase on or off from a single allosteric site via disulfide trapping(2011)156 cited
- → High‐Resolution Structural Characterization of a Helical α/β‐Peptide Foldamer Bound to the Anti‐Apoptotic Protein Bcl‐xL(2009)153 cited
- → Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody–Drug Conjugates(2017)146 cited
- → Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties(2021)144 cited