Yuji Iizawa
Publications by Year
Research Areas
HIV Research and Treatment, Immune Response and Inflammation, HIV/AIDS drug development and treatment, Antimicrobial Resistance in Staphylococcus, Immune Cell Function and Interaction
Most-Cited Works
- → A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity(1999)755 cited
- → A Novel Cyclohexene Derivative, Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), Selectively Inhibits Toll-Like Receptor 4-Mediated Cytokine Production through Suppression of Intracellular Signaling(2005)373 cited
- → TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain(2008)315 cited
- → Analysis of binding site for the novel small‐molecule TLR4 signal transduction inhibitor TAK‐242 and its therapeutic effect on mouse sepsis model(2009)241 cited
- → Role of tumor necrosis factor alpha in pathogenesis of pneumococcal pneumonia in mice(1997)177 cited
- → Therapeutic effects of TAK-242, a novel selective Toll-like receptor 4 signal transduction inhibitor, in mouse endotoxin shock model(2007)175 cited
- → TAK-599, a novel N-Phosphono type prodrug of anti-MRSA cephalosporin T-91825: synthesis, physicochemical and pharmacological properties(2003)135 cited
- → TAK-652 Inhibits CCR5-Mediated Human Immunodeficiency Virus Type 1 Infection In Vitro and Has Favorable Pharmacokinetics in Humans(2005)109 cited
- → Orally active CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological activities of 1-benzazepine derivatives containing a sulfoxide moiety(2004)101 cited
- → Therapeutic effect of cefozopran (SCE-2787), a new parenteral cephalosporin, against experimental infections in mice(1993)89 cited