Andy Cooke
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Growth Hormone and Insulin-like Growth Factors, Cancer-related Molecular Pathways, Liver physiology and pathology, Metabolism, Diabetes, and Cancer
Most-Cited Works
- → Preclinical Characterization of OSI-027, a Potent and Selective Inhibitor of mTORC1 and mTORC2: Distinct from Rapamycin(2011)200 cited
- → Calmodulin antagonists of improved potency and specificity for use in the study of calmodulin biochemistry(1988)50 cited
- → Discovery of Novel Insulin-Like Growth Factor-1 Receptor Inhibitors with Unique Time-Dependent Binding Kinetics(2013)17 cited
- → Potent and selective cyclohexyl-derived imidazopyrazine insulin-like growth factor 1 receptor inhibitors with in vivo efficacy(2010)16 cited
- → Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases(2013)15 cited
- → Discovery of an Orally Efficacious Imidazo[5,1-f][1,2,4]triazine Dual Inhibitor of IGF-1R and IR(2010)9 cited
- → Pilocarpine as Antagonist to the Undesired Effects of Ganglion-blocking Agents in Treatment of Hypertension(1954)8 cited
- In vivo evaluation of OSI-906, a novel small molecule kinase inhibitor of the insulin-like growth factor-1 receptor (IGF-1R)(2007)
- → Calmodulin antagonists of improved specificity and potency(1986)1 cited
- → Data from Preclinical Characterization of OSI-027, a Potent and Selective Inhibitor of mTORC1 and mTORC2: Distinct from Rapamycin(2023)