Bruno Alicke
Publications by Year
Research Areas
Hedgehog Signaling Pathway Studies, Glioma Diagnosis and Treatment, Lung Cancer Treatments and Mutations, Protein Degradation and Inhibitors, Chemical Reactions and Isotopes
Most-Cited Works
- → Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma(2009)841 cited
- → Small Molecule Inhibition of GDC-0449 Refractory Smoothened Mutants and Downstream Mechanisms of Drug Resistance(2010)363 cited
- → Novel Small Molecule Inhibitors of 3-Phosphoinositide-dependent Kinase-1(2005)225 cited
- → The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models(2006)178 cited
- → A cell identity switch allows residual BCC to survive Hedgehog pathway inhibition(2018)139 cited
- → Antitumor Activity of Targeted and Cytotoxic Agents in Murine Subcutaneous Tumor Models Correlates with Clinical Response(2012)130 cited
- → Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells(2011)118 cited
- → Pharmacokinetic–Pharmacodynamic Analysis of Vismodegib in Preclinical Models of Mutational and Ligand-Dependent Hedgehog Pathway Activation(2011)115 cited
- → Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR(2016)105 cited
- → PRC2-mediated repression of SMARCA2 predicts EZH2 inhibitor activity in SWI/SNF mutant tumors(2017)102 cited